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CARD14 Expression in Dermal Endothelial Cells in Psoriasis

Mutations in the caspase recruitment domain, family member 14 (CARD14) gene have recently been described in psoriasis patients, and explain the psoriasis susceptibility locus 2 (PSORS2). CARD14 is a scaffolding protein that regulates NF-κB activation, and psoriasis-associated CARD14 mutations lead t...

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Detalles Bibliográficos
Autores principales: Harden, Jamie L., Lewis, Steven M., Pierson, Katherine C., Suárez-Fariñas, Mayte, Lentini, Tim, Ortenzio, Francesca S., Zaba, Lisa C., Goldbach-Mansky, Raphaela, Bowcock, Anne M., Lowes, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219711/
https://www.ncbi.nlm.nih.gov/pubmed/25369198
http://dx.doi.org/10.1371/journal.pone.0111255