The Role of Apolipoprotein E as a Risk Factor for an Earlier Age at Onset for Machado-Joseph Disease Is Doubtful

Machado-Joseph disease (MJD) is an inherited neurodegenerative disease caused by an expanded CAG repeat in the ATXN3 gene. Although the principal genetic determinant of the age at onset (AAO) is the length of the expanded CAG repeat, the additional genetic contribution of MJD toward the AAO has most...

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Detalles Bibliográficos
Autores principales: Zhou, Qi, Ni, Wang, Dong, Yi, Wang, Ning, Gan, Shi-Rui, Wu, Zhi-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219713/
https://www.ncbi.nlm.nih.gov/pubmed/25369462
http://dx.doi.org/10.1371/journal.pone.0111356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219713/
https://www.ncbi.nlm.nih.gov/pubmed/25369462
http://dx.doi.org/10.1371/journal.pone.0111356

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