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CD161(+) MAIT Cells Are Severely Reduced in Peripheral Blood and Lymph Nodes of HIV-Infected Individuals Independently of Disease Progression

Mucosal-associated invariant T (MAIT) cells are characterized by the combined expression of the semi-invariant T cell receptor (TCR) Vα7.2, the lectin receptor CD161, as well as IL-18R, and play an important role in antibacterial host defense of the gut. The current study characterized CD161(+) MAIT...

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Detalles Bibliográficos
Autores principales: Eberhard, Johanna Maria, Hartjen, Philip, Kummer, Silke, Schmidt, Reinhold E., Bockhorn, Maximilian, Lehmann, Clara, Balagopal, Ashwin, Hauber, Joachim, van Lunzen, Jan, zur Wiesch, Julian Schulze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219715/
https://www.ncbi.nlm.nih.gov/pubmed/25369333
http://dx.doi.org/10.1371/journal.pone.0111323