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CD161(+) MAIT Cells Are Severely Reduced in Peripheral Blood and Lymph Nodes of HIV-Infected Individuals Independently of Disease Progression
Mucosal-associated invariant T (MAIT) cells are characterized by the combined expression of the semi-invariant T cell receptor (TCR) Vα7.2, the lectin receptor CD161, as well as IL-18R, and play an important role in antibacterial host defense of the gut. The current study characterized CD161(+) MAIT...
Autores principales: | Eberhard, Johanna Maria, Hartjen, Philip, Kummer, Silke, Schmidt, Reinhold E., Bockhorn, Maximilian, Lehmann, Clara, Balagopal, Ashwin, Hauber, Joachim, van Lunzen, Jan, zur Wiesch, Julian Schulze |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219715/ https://www.ncbi.nlm.nih.gov/pubmed/25369333 http://dx.doi.org/10.1371/journal.pone.0111323 |
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