How Difficult Is Inference of Mammalian Causal Gene Regulatory Networks?

Gene regulatory networks (GRNs) play a central role in systems biology, especially in the study of mammalian organ development. One key question remains largely unanswered: Is it possible to infer mammalian causal GRNs using observable gene co-expression patterns alone? We assembled two mouse GRN da...

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Detalles Bibliográficos
Autores principales: Djordjevic, Djordje, Yang, Andrian, Zadoorian, Armella, Rungrugeecharoen, Kevin, Ho, Joshua W. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219746/
https://www.ncbi.nlm.nih.gov/pubmed/25369032
http://dx.doi.org/10.1371/journal.pone.0111661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219746/
https://www.ncbi.nlm.nih.gov/pubmed/25369032
http://dx.doi.org/10.1371/journal.pone.0111661

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