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How Difficult Is Inference of Mammalian Causal Gene Regulatory Networks?
Gene regulatory networks (GRNs) play a central role in systems biology, especially in the study of mammalian organ development. One key question remains largely unanswered: Is it possible to infer mammalian causal GRNs using observable gene co-expression patterns alone? We assembled two mouse GRN da...
Autores principales: | Djordjevic, Djordje, Yang, Andrian, Zadoorian, Armella, Rungrugeecharoen, Kevin, Ho, Joshua W. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219746/ https://www.ncbi.nlm.nih.gov/pubmed/25369032 http://dx.doi.org/10.1371/journal.pone.0111661 |
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