Regulation of RAB5C Is Important for the Growth Inhibitory Effects of MiR-509 in Human Precursor-B Acute Lymphoblastic Leukemia

MicroRNAs (miRs) regulate essentially all cellular processes, but few miRs are known to inhibit growth of precursor-B acute lymphoblastic leukemias (B-ALLs). We identified miR-509 via a human genome-wide gain-of-function screen for miRs that inhibit growth of the NALM6 human B-ALL cell line. MiR-509...

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Detalles Bibliográficos
Autores principales: Tan, Yee Sun, Kim, MinJung, Kingsbury, Tami J., Civin, Curt I., Cheng, Wen-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219775/
https://www.ncbi.nlm.nih.gov/pubmed/25368993
http://dx.doi.org/10.1371/journal.pone.0111777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219775/
https://www.ncbi.nlm.nih.gov/pubmed/25368993
http://dx.doi.org/10.1371/journal.pone.0111777

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