A Hybrid Non-Ribosomal Peptide/Polyketide Synthetase Containing Fatty-Acyl Ligase (FAAL) Synthesizes the β-Amino Fatty Acid Lipopeptides Puwainaphycins in the Cyanobacterium Cylindrospermum alatosporum

A putative operon encoding the biosynthetic pathway for the cytotoxic cyanobacterial lipopeptides puwainphycins was identified in Cylindrospermum alatosporum. Bioinformatics analysis enabled sequential prediction of puwainaphycin biosynthesis; this process is initiated by the activation of a fatty a...

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Detalles Bibliográficos
Autores principales: Mareš, Jan, Hájek, Jan, Urajová, Petra, Kopecký, Jiří, Hrouzek, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219810/
https://www.ncbi.nlm.nih.gov/pubmed/25369527
http://dx.doi.org/10.1371/journal.pone.0111904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219810/
https://www.ncbi.nlm.nih.gov/pubmed/25369527
http://dx.doi.org/10.1371/journal.pone.0111904

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