Cargando…

A TIR Domain Protein from E. faecalis Attenuates MyD88-Mediated Signaling and NF-κB Activation

Toll-like receptor signaling, mediated by functional Toll/interleukin-1 receptor (TIR) domains, plays a critical role in activating the innate immune response responsible for controlling and clearing infection. Bacterial protein mimics of components of this signaling pathway have been identified and...

Descripción completa

Detalles Bibliográficos
Autores principales: Zou, Jun, Baghdayan, Arto S., Payne, Sarah J., Shankar, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219826/
https://www.ncbi.nlm.nih.gov/pubmed/25369374
http://dx.doi.org/10.1371/journal.pone.0112010