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A TIR Domain Protein from E. faecalis Attenuates MyD88-Mediated Signaling and NF-κB Activation
Toll-like receptor signaling, mediated by functional Toll/interleukin-1 receptor (TIR) domains, plays a critical role in activating the innate immune response responsible for controlling and clearing infection. Bacterial protein mimics of components of this signaling pathway have been identified and...
Autores principales: | Zou, Jun, Baghdayan, Arto S., Payne, Sarah J., Shankar, Nathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219826/ https://www.ncbi.nlm.nih.gov/pubmed/25369374 http://dx.doi.org/10.1371/journal.pone.0112010 |
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