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A TIR Domain Protein from E. faecalis Attenuates MyD88-Mediated Signaling and NF-κB Activation

Toll-like receptor signaling, mediated by functional Toll/interleukin-1 receptor (TIR) domains, plays a critical role in activating the innate immune response responsible for controlling and clearing infection. Bacterial protein mimics of components of this signaling pathway have been identified and...

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Detalles Bibliográficos
Autores principales: Zou, Jun, Baghdayan, Arto S., Payne, Sarah J., Shankar, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219826/
https://www.ncbi.nlm.nih.gov/pubmed/25369374
http://dx.doi.org/10.1371/journal.pone.0112010

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