Metabolic effect and receptor signalling profile of a non-metabolisable insulin glargine analogue

CONTEXT: Insulin glargine (GLA) is rapidly metabolized in vivo to metabolite M1, which has in vitro metabolic and mitogenic profiles comparable with human insulin (HI). OBJECTIVE: To investigate the pharmacologic and signalling profiles of a non-metabolizable analogue (A21Gly,DiD-Arg) insulin (D-GLA...

Descripción completa

Detalles Bibliográficos
Autores principales: Werner, Ulrich, Korn, Marcus, Schmidt, Ronald, Wendrich, Thomas M., Tennagels, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa UK Ltd. 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219851/
https://www.ncbi.nlm.nih.gov/pubmed/25144413
http://dx.doi.org/10.3109/13813455.2014.950589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219851/
https://www.ncbi.nlm.nih.gov/pubmed/25144413
http://dx.doi.org/10.3109/13813455.2014.950589

Ejemplares similares