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Mycobacterium tuberculosis PE25/PPE41 protein complex induces necrosis in macrophages: Role in virulence and disease reactivation?

Necrotic cell death during TB infection is an important prerequisite for bacterial dissemination and virulence. The underlying mechanisms and the bacterial factors involved therein are not well understood. The Mycobacterium tuberculosis (M. tuberculosis) co-operonic PE25/PPE41 protein complex, simil...

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Detalles Bibliográficos
Autores principales: Tundup, Smanla, Mohareer, Krishnaveni, Hasnain, Seyed E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219985/
https://www.ncbi.nlm.nih.gov/pubmed/25379378
http://dx.doi.org/10.1016/j.fob.2014.09.001