Epigenetic Modification Agents Improve Genomic Methylation Reprogramming in Porcine Cloned Embryos

Incomplete DNA methylation reprogramming in cloned embryos leads to low cloning efficiency. Our previous studies showed that the epigenetic modification agents 5-aza-2’-deoxycytidine (5-aza-dC) or trichostatin A (TSA) could enhance the developmental competence of porcine cloned embryos. Here, we inv...

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Detalles Bibliográficos
Autores principales: HUAN, Yan Jun, ZHU, Jiang, WANG, Hong Mei, WU, Zhan Feng, ZHANG, Ji Guang, XIE, Bing Teng, LI, Jing Yu, KONG, Qing Ran, LIU, Zhong Hua, HE, Hong Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219995/
https://www.ncbi.nlm.nih.gov/pubmed/25047549
http://dx.doi.org/10.1262/jrd.2014-062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219995/
https://www.ncbi.nlm.nih.gov/pubmed/25047549
http://dx.doi.org/10.1262/jrd.2014-062

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