Deletion and deletion/insertion mutations in the juxtamembrane domain of the FLT3 gene in adult acute myeloid leukemia

In contrast to FLT3 ITD mutations, in-frame deletions in the FLT3 gene have rarely been described in adult acute leukemia. We report two cases of AML with uncommon in-frame mutations in the juxtamembrane domain of the FLT3 gene: a 3-bp (c.1770_1774delCTACGinsGT; p.F590_V592delinsLF) deletion/inserti...

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Detalles Bibliográficos
Autores principales: Deeb, Kristin K., Smonskey, Matthew T., DeFedericis, HanChun, Deeb, George, Sait, Sheila N.J., Wetzler, Meir, Wang, Eunice S., Starostik, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220013/
https://www.ncbi.nlm.nih.gov/pubmed/25379410
http://dx.doi.org/10.1016/j.lrr.2013.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220013/
https://www.ncbi.nlm.nih.gov/pubmed/25379410
http://dx.doi.org/10.1016/j.lrr.2013.09.003

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