Dissecting conformational contributions to glycosidase catalysis and inhibition

Glycoside hydrolases (GHs) are classified into >100 sequence-based families. These enzymes process a wide variety of complex carbohydrates with varying stereochemistry at the anomeric and other ring positions. The shapes that these sugars adopt upon binding to their cognate GHs, and the conformat...

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Detalles Bibliográficos
Autores principales: Speciale, Gaetano, Thompson, Andrew J, Davies, Gideon J, Williams, Spencer J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220041/
https://www.ncbi.nlm.nih.gov/pubmed/25016573
http://dx.doi.org/10.1016/j.sbi.2014.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220041/
https://www.ncbi.nlm.nih.gov/pubmed/25016573
http://dx.doi.org/10.1016/j.sbi.2014.06.003

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