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Leucine Modulates Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes

Previous studies from this laboratory demonstrate that dietary leucine protects against high fat diet-induced mitochondrial impairments and stimulates mitochondrial biogenesis and energy partitioning from adipocytes to muscle cells through SIRT1-mediated mechanisms. Moreover, β-hydroxy-β-methyl buty...

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Detalles Bibliográficos
Autores principales: Liang, Chunzi, Curry, Benjamin J., Brown, Patricia L., Zemel, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220583/
https://www.ncbi.nlm.nih.gov/pubmed/25400942
http://dx.doi.org/10.1155/2014/239750