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Segregation of a QTL cluster for home-cage activity using a new mapping method based on regression analysis of congenic mouse strains

Recent genetic studies have shown that genetic loci with significant effects in whole-genome quantitative trait loci (QTL) analyses were lost or weakened in congenic strains. Characterisation of the genetic basis of this attenuated QTL effect is important to our understanding of the genetic mechanis...

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Detalles Bibliográficos
Autores principales: Kato, S, Ishii, A, Nishi, A, Kuriki, S, Koide, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220717/
https://www.ncbi.nlm.nih.gov/pubmed/24781804
http://dx.doi.org/10.1038/hdy.2014.42