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Increased expression of T cell immunoglobulin and mucin domain 3 aggravates brain inflammation via regulation of the function of microglia/macrophages after intracerebral hemorrhage in mice

BACKGROUND: Microglia/macrophages are known to play important roles in initiating brain inflammation after spontaneous intracerebral hemorrhage (ICH). T cell immunoglobulin and mucin domain-3 (Tim-3) have been proven to play a critical part in several inflammatory diseases through regulation of both...

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Detalles Bibliográficos
Autores principales: Xu, ChangJun, Wang, Tao, Cheng, Si, Liu, YuGuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220802/
https://www.ncbi.nlm.nih.gov/pubmed/24289479
http://dx.doi.org/10.1186/1742-2094-10-141