Neurovascular unit dysfunction with blood-brain barrier hyperpermeability contributes to major depressive disorder: a review of clinical and experimental evidence

About one-third of people with major depressive disorder (MDD) fail at least two antidepressant drug trials at 1 year. Together with clinical and experimental evidence indicating that the pathophysiology of MDD is multifactorial, this observation underscores the importance of elucidating mechanisms...

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Detalles Bibliográficos
Autores principales: Najjar, Souhel, Pearlman, Daniel M, Devinsky, Orrin, Najjar, Amanda, Zagzag, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220803/
https://www.ncbi.nlm.nih.gov/pubmed/24289502
http://dx.doi.org/10.1186/1742-2094-10-142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220803/
https://www.ncbi.nlm.nih.gov/pubmed/24289502
http://dx.doi.org/10.1186/1742-2094-10-142

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