Activation of microglia induces symptoms of Parkinson’s disease in wild-type, but not in IL-1 knockout mice

BACKGROUND: Parkinson’s disease (PD) is an age-related progressive neurodegenerative disorder caused by selective loss of dopaminergic neurons from the substantia nigra (SN) to the striatum. The initial factor that triggers neurodegeneration is unknown; however, inflammation has been demonstrated to...

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Detalles Bibliográficos
Autores principales: Tanaka, Sachiko, Ishii, Atsuko, Ohtaki, Hirokazu, Shioda, Seiji, Yoshida, Takemi, Numazawa, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220804/
https://www.ncbi.nlm.nih.gov/pubmed/24289537
http://dx.doi.org/10.1186/1742-2094-10-143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220804/
https://www.ncbi.nlm.nih.gov/pubmed/24289537
http://dx.doi.org/10.1186/1742-2094-10-143

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