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Mutated Ca(V)2.1 channels dysregulate CASK/P2X3 signaling in mouse trigeminal sensory neurons of R192Q Cacna1a knock-in mice

BACKGROUND: ATP-gated P2X3 receptors of sensory ganglion neurons are important transducers of pain as they adapt their expression and function in response to acute and chronic nociceptive signals. The present study investigated the role of calcium/calmodulin-dependent serine protein kinase (CASK) in...

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Detalles Bibliográficos
Autores principales: Gnanasekaran, Aswini, Bele, Tanja, Hullugundi, Swathi, Simonetti, Manuela, Ferrari, Michael D, van den Maagdenberg, Arn MJM, Nistri, Andrea, Fabbretti, Elsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220808/
https://www.ncbi.nlm.nih.gov/pubmed/24294842
http://dx.doi.org/10.1186/1744-8069-9-62