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Mutated Ca(V)2.1 channels dysregulate CASK/P2X3 signaling in mouse trigeminal sensory neurons of R192Q Cacna1a knock-in mice
BACKGROUND: ATP-gated P2X3 receptors of sensory ganglion neurons are important transducers of pain as they adapt their expression and function in response to acute and chronic nociceptive signals. The present study investigated the role of calcium/calmodulin-dependent serine protein kinase (CASK) in...
Autores principales: | Gnanasekaran, Aswini, Bele, Tanja, Hullugundi, Swathi, Simonetti, Manuela, Ferrari, Michael D, van den Maagdenberg, Arn MJM, Nistri, Andrea, Fabbretti, Elsa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220808/ https://www.ncbi.nlm.nih.gov/pubmed/24294842 http://dx.doi.org/10.1186/1744-8069-9-62 |
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