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Rational Design of Superoxide Dismutase (SOD) Mimics: The Evaluation of the Therapeutic Potential of New Cationic Mn Porphyrins with Linear and Cyclic Substituents

[Image: see text] Our goal herein has been to gain further insight into the parameters which control porphyrin therapeutic potential. Mn porphyrins (MnTnOct-2-PyP(5+), MnTnHexOE-2-PyP(5+), MnTE-2-PyPhP(5+), and MnTPhE-2-PyP(5+)) that bear the same positive charge and same number of carbon atoms at m...

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Detalles Bibliográficos
Autores principales: Tovmasyan, Artak, Carballal, Sebastian, Ghazaryan, Robert, Melikyan, Lida, Weitner, Tin, Maia, Clarissa G. C., Reboucas, Julio S., Radi, Rafael, Spasojevic, Ivan, Benov, Ludmil, Batinic-Haberle, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220860/
https://www.ncbi.nlm.nih.gov/pubmed/25333724
http://dx.doi.org/10.1021/ic501329p