Caspase-3 Mediates the Pathogenic Effect of Yersinia pestis YopM in Liver of C57BL/6 Mice and Contributes to YopM's Function in Spleen

The virulence protein YopM of the plague bacterium Yersinia pestis has different dominant effects in liver and spleen. Previous studies focused on spleen, where YopM inhibits accumulation of inflammatory dendritic cells. In the present study we focused on liver, where PMN function may be directly un...

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Detalles Bibliográficos
Autores principales: Ye, Zhan, Gorman, Amanda A., Uittenbogaard, Annette M., Myers-Morales, Tanya, Kaplan, Alan M., Cohen, Donald A., Straley, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220956/
https://www.ncbi.nlm.nih.gov/pubmed/25372388
http://dx.doi.org/10.1371/journal.pone.0110956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220956/
https://www.ncbi.nlm.nih.gov/pubmed/25372388
http://dx.doi.org/10.1371/journal.pone.0110956

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