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Caspase-3 Mediates the Pathogenic Effect of Yersinia pestis YopM in Liver of C57BL/6 Mice and Contributes to YopM's Function in Spleen
The virulence protein YopM of the plague bacterium Yersinia pestis has different dominant effects in liver and spleen. Previous studies focused on spleen, where YopM inhibits accumulation of inflammatory dendritic cells. In the present study we focused on liver, where PMN function may be directly un...
Autores principales: | Ye, Zhan, Gorman, Amanda A., Uittenbogaard, Annette M., Myers-Morales, Tanya, Kaplan, Alan M., Cohen, Donald A., Straley, Susan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220956/ https://www.ncbi.nlm.nih.gov/pubmed/25372388 http://dx.doi.org/10.1371/journal.pone.0110956 |
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