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The MluI Cell Cycle Box (MCB) Motifs, but Not Damage-Responsive Elements (DREs), Are Responsible for the Transcriptional Induction of the rhp51 (+) Gene in Response to DNA Replication Stress

DNA replication stress induces the transcriptional activation of rhp51 (+), a fission yeast recA homolog required for repair of DNA double strand breaks. However, the mechanism by which DNA replication stress activates rhp51 (+) transcription is not understood. The promoter region of rhp51 (+) conta...

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Detalles Bibliográficos
Autores principales: Sartagul, Wugangerile, Zhou, Xin, Yamada, Yuki, Ma, Ning, Tanaka, Katsunori, Furuyashiki, Tomoyuki, Ma, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221157/
https://www.ncbi.nlm.nih.gov/pubmed/25372384
http://dx.doi.org/10.1371/journal.pone.0111936