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The MluI Cell Cycle Box (MCB) Motifs, but Not Damage-Responsive Elements (DREs), Are Responsible for the Transcriptional Induction of the rhp51 (+) Gene in Response to DNA Replication Stress
DNA replication stress induces the transcriptional activation of rhp51 (+), a fission yeast recA homolog required for repair of DNA double strand breaks. However, the mechanism by which DNA replication stress activates rhp51 (+) transcription is not understood. The promoter region of rhp51 (+) conta...
Autores principales: | Sartagul, Wugangerile, Zhou, Xin, Yamada, Yuki, Ma, Ning, Tanaka, Katsunori, Furuyashiki, Tomoyuki, Ma, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221157/ https://www.ncbi.nlm.nih.gov/pubmed/25372384 http://dx.doi.org/10.1371/journal.pone.0111936 |
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