Computational and Functional Characterization of Angiogenin Mutations, and Correlation with Amyotrophic Lateral Sclerosis

The Angiogenin (ANG) gene is frequently mutated in patients suffering from the neurodegenerative disease - amyotrophic lateral sclerosis (ALS). Most of the ALS-causing mutations in Angiogenin affect either its ribonucleolytic or nuclear translocation activity. Here we report the functional character...

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Detalles Bibliográficos
Autores principales: Padhi, Aditya K., Banerjee, Kamalika, Gomes, James, Banerjee, Manidipa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221194/
https://www.ncbi.nlm.nih.gov/pubmed/25372031
http://dx.doi.org/10.1371/journal.pone.0111963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221194/
https://www.ncbi.nlm.nih.gov/pubmed/25372031
http://dx.doi.org/10.1371/journal.pone.0111963

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