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Bi-Epitope SPR Surfaces: A Solution to Develop Robust Immunoassays

Surface plasmon resonance (SPR)-based immunoassays have numerous applications and require high affinity reagents for sensitive and reliable measurements. We describe a quick approach to turn low affinity antibodies into appropriate capture reagents. We used antibodies recognizing human ephrin type A...

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Detalles Bibliográficos
Autores principales: Peng, Li, Damschroder, Melissa M., Wu, Herren, Dall’Acqua, William F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221230/
https://www.ncbi.nlm.nih.gov/pubmed/25372291
http://dx.doi.org/10.1371/journal.pone.0112070