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Myeloid expression of angiotensin converting enzyme facilitates myeloid maturation and inhibits the development of myeloid-derived suppressor cells
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells which accumulate in cancer, infection and chronic inflammation. These cells suppress T cell function and the immune response. Angiotensin converting enzyme (ACE) is a peptidase that is now known to regu...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221240/ https://www.ncbi.nlm.nih.gov/pubmed/24614194 http://dx.doi.org/10.1038/labinvest.2014.41 |