MacroH2A1.1 and PARP-1 cooperate to regulate transcription by promoting CBP-mediated H2B acetylation

The histone variant macroH2A1 regulates gene expression important for differentiation, stem cell reprogramming and tumor suppression. Here, we demonstrate that in primary human cells, macroH2A1 participates in two physically and functionally distinct types of chromatin either marked by H3K27me3 or n...

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Detalles Bibliográficos
Autores principales: Chen, Hongshan, Ruiz, Penelope D., Novikov, Leonid, Casill, Alyssa D., Park, Jong Woo, Gamble, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221384/
https://www.ncbi.nlm.nih.gov/pubmed/25306110
http://dx.doi.org/10.1038/nsmb.2903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221384/
https://www.ncbi.nlm.nih.gov/pubmed/25306110
http://dx.doi.org/10.1038/nsmb.2903

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