Cargando…

MacroH2A1.1 and PARP-1 cooperate to regulate transcription by promoting CBP-mediated H2B acetylation

The histone variant macroH2A1 regulates gene expression important for differentiation, stem cell reprogramming and tumor suppression. Here, we demonstrate that in primary human cells, macroH2A1 participates in two physically and functionally distinct types of chromatin either marked by H3K27me3 or n...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Hongshan, Ruiz, Penelope D., Novikov, Leonid, Casill, Alyssa D., Park, Jong Woo, Gamble, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221384/ https://www.ncbi.nlm.nih.gov/pubmed/25306110 http://dx.doi.org/10.1038/nsmb.2903

Ejemplares similares

MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20
por: Ruiz, Penelope D., et al.
Publicado: (2018)

Phosphorylation within Intrinsic Disordered Region Discriminates Histone Variant macroH2A1 Splicing Isoforms—macroH2A1.1 and macroH2A1.2
por: Giallongo, Sebastiano, et al.
Publicado: (2021)

The MacroH2A1.1 – PARP1 Axis at the Intersection Between Stress Response and Metabolism
por: Hurtado-Bagès, Sarah, et al.
Publicado: (2018)

MacroH2A1 Immunoexpression in Breast Cancer
por: Broggi, Giuseppe, et al.
Publicado: (2020)

Histone macroH2A1 is a stronger regulator of hippocampal transcription and memory than macroH2A2 in mice
por: Singh, Gurdeep, et al.
Publicado: (2022)

The macroH2A1.2 histone variant links ATRX loss to alternative telomere lengthening.
por: Kim, Jeongkyu, et al.
Publicado: (2019)

X Chromosome Inactivation and Differentiation Occur Readily in ES Cells Doubly-Deficient for MacroH2A1 and MacroH2A2
por: Tanasijevic, Borko, et al.
Publicado: (2011)

MacroH2A1 Regulation of Poly(ADP-Ribose) Synthesis and Stability Prevents Necrosis and Promotes DNA Repair
por: Ruiz, Penelope D., et al.
Publicado: (2019)

Author Correction: Histone macroH2A1 is a stronger regulator of hippocampal transcription and memory than macroH2A2 in mice
por: Singh, Gurdeep, et al.
Publicado: (2022)

MacroH2A1.2 Inhibits Prostate Cancer-induced Osteoclastogenesis through Cooperation with HP1α and H1.2
por: Kim, Jinman, et al.
Publicado: (2018)

The Histone H2A Variant MacroH2A1 Does Not Localize to the Centrosome
por: Friedman, Nathalie, et al.
Publicado: (2011)

Histone Variant MacroH2A1 Plays an Isoform-Specific Role in Suppressing Epithelial-Mesenchymal Transition
por: Hodge, Dayle Q., et al.
Publicado: (2018)

The Role of MacroH2A Histone Variants in Cancer
por: Hsu, Chen-Jen, et al.
Publicado: (2021)

MacroH2A1 knockdown effects on the Peg3 imprinted domain
por: Choo, Jung Ha, et al.
Publicado: (2007)

macroH2A1 histone variant represses rDNA transcription
por: Cong, Rong, et al.
Publicado: (2014)

MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD(+) consumption
por: Posavec Marjanović, Melanija, et al.
Publicado: (2017)

Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis
por: Pazienza, Valerio, et al.
Publicado: (2016)

macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma
por: Nikolic, Ana, et al.
Publicado: (2023)

Deficiency of histone variant macroH2A1.1 is associated with sexually dimorphic obesity in mice
por: Chiodi, Valentina, et al.
Publicado: (2023)

Histone variant macroH2A1 deletion in mice causes female-specific steatosis
por: Boulard, Mathieu, et al.
Publicado: (2010)

Immunopositivity for Histone MacroH2A1 Isoforms Marks Steatosis-Associated Hepatocellular Carcinoma
por: Rappa, Francesca, et al.
Publicado: (2013)

Histone variant macroH2A confers resistance to nuclear reprogramming
por: Pasque, Vincent, et al.
Publicado: (2011)

LSH mediates gene repression through macroH2A deposition
por: Ni, Kai, et al.
Publicado: (2020)

SIRT1-metabolite binding histone macroH2A1.1 protects hepatocytes against lipid accumulation
por: Pazienza, Valerio, et al.
Publicado: (2014)

Correction: Immunopositivity for Histone MacroH2A1 Isoforms Marks Steatosis-Associated Hepatocellular Carcinoma
por: Rappa, Francesca, et al.
Publicado: (2013)

MacroH2A1 associates with nuclear lamina and maintains chromatin architecture in mouse liver cells
por: Fu, Yuhua, et al.
Publicado: (2015)

Histone variant MacroH2A1 is downregulated in prostate cancer and influences malignant cell phenotype
por: Vieira-Silva, Tânia Soraia, et al.
Publicado: (2019)

Loss of macroH2A1 decreases mitochondrial metabolism and reduces the aggressiveness of uveal melanoma cells
por: Giallongo, Sebastiano, et al.
Publicado: (2020)

Human macroH2A1 drives nucleosome dephasing and genome instability in histone-humanized yeast
por: Haase, Max A. B., et al.
Publicado: (2023)

Deficiency of 15-LOX-1 Induces Radioresistance through Downregulation of MacroH2A2 in Colorectal Cancer
por: Na, Yoo Jin, et al.
Publicado: (2019)

The Linker Region of MacroH2A Promotes Self-association of Nucleosomal Arrays
por: Muthurajan, Uma M., et al.
Publicado: (2011)

Transcription-associated histone pruning demarcates macroH2A chromatin domains
por: Sun, Zhen, et al.
Publicado: (2018)

Zebrafish macroH2A variants have distinct embryo localization and function
por: Gonzalez-Munoz, E., et al.
Publicado: (2019)

Retargeting of macroH2A following mitosis to cytogenetic-scale heterochromatic domains
por: Sato, Hanae, et al.
Publicado: (2019)

Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice
por: Kim, Sanghyun P., et al.
Publicado: (2021)

Increased macroH2A1.1 Expression Correlates with Poor Survival of Triple-Negative Breast Cancer Patients
por: Lavigne, Anne-Claire, et al.
Publicado: (2014)

Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome
por: Bereshchenko, Oxana, et al.
Publicado: (2019)

QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis
por: Li, Feng, et al.
Publicado: (2016)

Histone MacroH2A1: A Chromatin Point of Intersection between Fasting, Senescence and Cellular Regeneration
por: Lo Re, Oriana, et al.
Publicado: (2017)

Cell cycle–dependent localization of macroH2A in chromatin of the inactive X chromosome
por: Chadwick, Brian P., et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_ksbvaf95nh34bi6r30uo83oc2f