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A Novel Gain-Of-Function Mutation of the Proneural IRX1 and IRX2 Genes Disrupts Axis Elongation in the Araucana Rumpless Chicken

Axis elongation of the vertebrate embryo involves the generation of cell lineages from posterior progenitor populations. We investigated the molecular mechanism governing axis elongation in vertebrates using the Araucana rumpless chicken. Araucana embryos exhibit a defect in axis elongation, failing...

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Detalles Bibliográficos
Autores principales: Freese, Nowlan H., Lam, Brianna A., Staton, Meg, Scott, Allison, Chapman, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221472/
https://www.ncbi.nlm.nih.gov/pubmed/25372603
http://dx.doi.org/10.1371/journal.pone.0112364