Docking study of novel antihyperlipidemic thieno[2,3-d]pyrimidine; LM-1554, with some molecular targets related to hyperlipidemia - an investigation into its mechanism of action

An investigation into the mechanism of antihyperlipidemic action of 2-chloromethyl-5,6,7,8-tetrahydrobenzo(b)thieno[2,3-d]pyrimidin-4(3H)-one (LM-1554) was carried out through docking experiments with six different molecular targets; Niemann Pick C1 Like1 protein (NPC1L1), ATP citrate lyase (ACL), C...

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Detalles Bibliográficos
Autores principales: Khedkar, Vijay M, Arya, Nikhilesh, Coutinho, Evans C, Shishoo, Chamanlal J, Jain, Kishor S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221561/
https://www.ncbi.nlm.nih.gov/pubmed/25392798
http://dx.doi.org/10.1186/2193-1801-3-628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221561/
https://www.ncbi.nlm.nih.gov/pubmed/25392798
http://dx.doi.org/10.1186/2193-1801-3-628

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