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New Technologies Provide Quantum Changes in the Scale, Speed, and Success of SELEX Methods and Aptamer Characterization

Single-stranded oligonucleotide aptamers have attracted great attention in the past decade because of their diagnostic and therapeutic potential. These versatile, high affinity and specificity reagents are selected by an iterative in vitro process called SELEX, Systematic Evolution of Ligands by Exp...

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Detalles Bibliográficos
Autores principales: Ozer, Abdullah, Pagano, John M, Lis, John T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221594/
https://www.ncbi.nlm.nih.gov/pubmed/25093707
http://dx.doi.org/10.1038/mtna.2014.34