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A Cancer Cell-Activatable Aptamer-Reporter System for One-Step Assay of Circulating Tumor Cells

The current antibody-mediated numeration assays of circulating tumor cells (CTCs) require multiple steps and are time-consuming. To overcome these technical limitations, a cancer cell-activatable aptamer-reporter was formulated by conjugating a biomarker-specific aptamer sequence with paired fluoroc...

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Detalles Bibliográficos
Autores principales: Zeng, Zihua, Tung, Ching-Hsuan, Zu, Youli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221596/
https://www.ncbi.nlm.nih.gov/pubmed/25118170
http://dx.doi.org/10.1038/mtna.2014.36