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A Cancer Cell-Activatable Aptamer-Reporter System for One-Step Assay of Circulating Tumor Cells
The current antibody-mediated numeration assays of circulating tumor cells (CTCs) require multiple steps and are time-consuming. To overcome these technical limitations, a cancer cell-activatable aptamer-reporter was formulated by conjugating a biomarker-specific aptamer sequence with paired fluoroc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221596/ https://www.ncbi.nlm.nih.gov/pubmed/25118170 http://dx.doi.org/10.1038/mtna.2014.36 |