[Pt(O,O’-acac)(γ-acac)(DMS)] Alters SH-SY5Y Cell Migration and Invasion by the Inhibition of Na(+)/H(+) Exchanger Isoform 1 Occurring through a PKC-ε/ERK/mTOR Pathway

We previously showed that [Pt(O,O’-acac)(γ-acac)(DMS)] ([Pt(acac)(2)(DMS)]) exerted substantial cytotoxic effects in SH-SY5Y neuroblastoma cells, and decreased metalloproteases (MMPs) production and cells migration in MCF-7 breast cancer cells. The ubiquitously distributed sodium-hydrogen antiporter...

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Detalles Bibliográficos
Autores principales: Muscella, Antonella, Vetrugno, Carla, Calabriso, Nadia, Cossa, Luca Giulio, De Pascali, Sandra Angelica, Fanizzi, Francesco Paolo, Marsigliante, Santo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221608/
https://www.ncbi.nlm.nih.gov/pubmed/25372487
http://dx.doi.org/10.1371/journal.pone.0112186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221608/
https://www.ncbi.nlm.nih.gov/pubmed/25372487
http://dx.doi.org/10.1371/journal.pone.0112186

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