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Cholesterol: A modulator of the phagocyte NADPH oxidase activity - A cell-free study

The NADPH oxidase Nox2, a multi-subunit enzyme complex comprising membrane and cytosolic proteins, catalyzes a very intense production of superoxide ions O(2)(•−), which are transformed into other reactive oxygen species (ROS). In vitro, it has to be activated by addition of amphiphiles like arachid...

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Detalles Bibliográficos
Autores principales: Masoud, Rawand, Bizouarn, Tania, Houée-Levin, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221629/
https://www.ncbi.nlm.nih.gov/pubmed/25462061
http://dx.doi.org/10.1016/j.redox.2014.10.001