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Cholesterol: A modulator of the phagocyte NADPH oxidase activity - A cell-free study
The NADPH oxidase Nox2, a multi-subunit enzyme complex comprising membrane and cytosolic proteins, catalyzes a very intense production of superoxide ions O(2)(•−), which are transformed into other reactive oxygen species (ROS). In vitro, it has to be activated by addition of amphiphiles like arachid...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221629/ https://www.ncbi.nlm.nih.gov/pubmed/25462061 http://dx.doi.org/10.1016/j.redox.2014.10.001 |