The Application of Gaussian Mixture Models for Signal Quantification in MALDI-ToF Mass Spectrometry of Peptides

Matrix assisted laser desorption/ionization time-of-flight (MALDI-TOF) coupled with stable isotope standards (SIS) has been used to quantify native peptides. This peptide quantification by MALDI-TOF approach has difficulties quantifying samples containing peptides with ion currents in overlapping sp...

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Detalles Bibliográficos
Autores principales: Spainhour, John Christian G., Janech, Michael G., Schwacke, John H., Velez, Juan Carlos Q., Ramakrishnan, Viswanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221630/
https://www.ncbi.nlm.nih.gov/pubmed/25372836
http://dx.doi.org/10.1371/journal.pone.0111016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221630/
https://www.ncbi.nlm.nih.gov/pubmed/25372836
http://dx.doi.org/10.1371/journal.pone.0111016

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