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A putative pH-dependent nuclear localization signal in the juxtamembrane region of c-Met

The C-terminal fragment of the c-Met receptor tyrosine kinase is present in the nuclei of some cells irrespective of ligand stimulation, but the responsible nuclear localization signal (NLS) has not been previously reported. Here, we report that two histidine residues separated by a 10-amino-acid sp...

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Detalles Bibliográficos
Autores principales: Chaudhary, Shubhash Chandra, Cho, Min-Guk, Nguyen, Tuyet Thi, Park, Kyu-Sang, Kwon, Myung-Hee, Lee, Jae-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221695/
https://www.ncbi.nlm.nih.gov/pubmed/25341359
http://dx.doi.org/10.1038/emm.2014.67