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A role for Rab27 in neutrophil chemotaxis and lung recruitment

BACKGROUND: Neutrophils are a critical part of the innate immune system. Their ability to migrate into infected or injured tissues precedes their role in microbial killing and clearance. We have previously shown that Rab27a can promote neutrophil migration by facilitating uropod release through prot...

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Detalles Bibliográficos
Autores principales: Singh, Rajesh K, Furze, Rebecca C, Birrell, Mark A, Rankin, Sara M, Hume, Alistair N, Seabra, Miguel C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221698/
https://www.ncbi.nlm.nih.gov/pubmed/25359237
http://dx.doi.org/10.1186/s12860-014-0039-z