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Elevated CXCL1 expression in breast cancer stroma predicts poor prognosis and is inversely associated with expression of TGF-β signaling proteins

BACKGROUND: CXCL1 is a chemotactic cytokine shown to regulate breast cancer progression and chemo-resistance. However, the prognostic significance of CXCL1 expression in breast cancer has not been fully characterized. Fibroblasts are important cellular components of the breast tumor microenvironment...

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Detalles Bibliográficos
Autores principales: Zou, An, Lambert, Diana, Yeh, Henry, Yasukawa, Ken, Behbod, Fariba, Fan, Fang, Cheng, Nikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221705/
https://www.ncbi.nlm.nih.gov/pubmed/25344051
http://dx.doi.org/10.1186/1471-2407-14-781