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Expression profile of Caenorhabditis elegans mutant for the Werner syndrome gene ortholog reveals the impact of vitamin C on development to increase life span

BACKGROUND: Werner Syndrome (WS) is a rare disorder characterized by the premature onset of a number of age-related diseases. The gene responsible for WS encodes a DNA helicase/exonuclease protein believed to affect different aspects of transcription, replication, and DNA repair. Caenorhabditis eleg...

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Detalles Bibliográficos
Autores principales: Dallaire, Alexandra, Proulx, Sophie, Simard, Martin J, Lebel, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221712/
https://www.ncbi.nlm.nih.gov/pubmed/25346348
http://dx.doi.org/10.1186/1471-2164-15-940