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Expression profile of Caenorhabditis elegans mutant for the Werner syndrome gene ortholog reveals the impact of vitamin C on development to increase life span
BACKGROUND: Werner Syndrome (WS) is a rare disorder characterized by the premature onset of a number of age-related diseases. The gene responsible for WS encodes a DNA helicase/exonuclease protein believed to affect different aspects of transcription, replication, and DNA repair. Caenorhabditis eleg...
Autores principales: | Dallaire, Alexandra, Proulx, Sophie, Simard, Martin J, Lebel, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221712/ https://www.ncbi.nlm.nih.gov/pubmed/25346348 http://dx.doi.org/10.1186/1471-2164-15-940 |
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