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Trithorax maintains the functional heterogeneity of neural stem cells through the transcription factor Buttonhead

The mechanisms that maintain the functional heterogeneity of stem cells, which generates diverse differentiated cell types required for organogenesis, are not understood. In this study, we report that Trithorax (Trx) actively maintains the heterogeneity of neural stem cells (neuroblasts) in the deve...

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Detalles Bibliográficos
Autores principales: Komori, Hideyuki, Xiao, Qi, Janssens, Derek H, Dou, Yali, Lee, Cheng-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221733/
https://www.ncbi.nlm.nih.gov/pubmed/25285447
http://dx.doi.org/10.7554/eLife.03502