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Flattop regulates basal body docking and positioning in mono- and multiciliated cells

Planar cell polarity (PCP) regulates basal body (BB) docking and positioning during cilia formation, but the underlying mechanisms remain elusive. In this study, we investigate the uncharacterized gene Flattop (Fltp) that is transcriptionally activated during PCP acquisition in ciliated tissues. Flt...

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Detalles Bibliográficos
Autores principales: Gegg, Moritz, Böttcher, Anika, Burtscher, Ingo, Hasenoeder, Stefan, Van Campenhout, Claude, Aichler, Michaela, Walch, Axel, Grant, Seth G N, Lickert, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221739/
https://www.ncbi.nlm.nih.gov/pubmed/25296022
http://dx.doi.org/10.7554/eLife.03842