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Phenylalanine sensitive K562-D cells for the analysis of the biochemical impact of excess amino acid

Although it is recognized that the abnormal accumulation of amino acid is a cause of the symptoms in metabolic disease such as phenylketonuria (PKU), the relationship between disease severity and serum amino acid levels is not well understood due to the lack of experimental model. Here, we present a...

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Detalles Bibliográficos
Autores principales: Sanayama, Yoshitami, Matsumoto, Akio, Shimojo, Naoki, Kohno, Yoichi, Nakaya, Haruaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221789/
https://www.ncbi.nlm.nih.gov/pubmed/25373594
http://dx.doi.org/10.1038/srep06941