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Phenylalanine sensitive K562-D cells for the analysis of the biochemical impact of excess amino acid
Although it is recognized that the abnormal accumulation of amino acid is a cause of the symptoms in metabolic disease such as phenylketonuria (PKU), the relationship between disease severity and serum amino acid levels is not well understood due to the lack of experimental model. Here, we present a...
Autores principales: | Sanayama, Yoshitami, Matsumoto, Akio, Shimojo, Naoki, Kohno, Yoichi, Nakaya, Haruaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221789/ https://www.ncbi.nlm.nih.gov/pubmed/25373594 http://dx.doi.org/10.1038/srep06941 |
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