Pentameric Thiophene-Based Ligands that Spectrally Discriminate Amyloid-β and Tau Aggregates Display Distinct Solvatochromism and Viscosity-Induced Spectral Shifts

A wide range of neurodegenerative diseases are characterized by the deposition of multiple protein aggregates. Ligands for molecular characterization and discrimination of these pathological hallmarks are thus important for understanding their potential role in pathogenesis as well as for clinical d...

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Detalles Bibliográficos
Autores principales: Simon, Rozalyn A, Shirani, Hamid, Åslund, K O Andreas, Bäck, Marcus, Haroutunian, Vahram, Gandy, Sam, Nilsson, K Peter R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221846/
https://www.ncbi.nlm.nih.gov/pubmed/25111601
http://dx.doi.org/10.1002/chem.201402890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221846/
https://www.ncbi.nlm.nih.gov/pubmed/25111601
http://dx.doi.org/10.1002/chem.201402890

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