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The efficacy of cetuximab in a tissue-engineered three-dimensional in vitro model of colorectal cancer
The preclinical development process of chemotherapeutic drugs is often carried out in two-dimensional monolayer cultures. However, a considerable amount of evidence demonstrates that two-dimensional cell culture does not accurately reflect the three-dimensional in vivo tumour microenvironment, speci...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221936/ https://www.ncbi.nlm.nih.gov/pubmed/25383169 http://dx.doi.org/10.1177/2041731414544183 |